Prostate cancer

Prostate cancer

Prostate

Facts about Prostate Cancer

  • About 1 man in 7 will be diagnosed with prostate cancer during his lifetime.
  • Prostate cancer is the second leading cause of cancer death in American men, behind only lung cancer. About 1 man in 39 will die of prostate cancer.
  • An estimated 1.1 million men worldwide were diagnosed with prostate cancer in 2012, accounting for 15% of the cancers diagnosed in men, with almost 70% of the cases (759,000) occurring in more developed regions.
  • With an estimated 307,000 deaths in 2012, prostate cancer is the fifth leading cause of death from cancer in men (6.6% of the total men deaths).

Research scope in Prostate Cancer

  • Apparent diffusion coefficient (ADC) vales measurement may be a useful imaging biomarker for prediction and early assessment of therapeutic response of prostate cancer to carbon-ion radiotherapy (CIRT)…more
  • Abiraterone Acetate efficacy may exert an HSP27 suppressive role that goes beyond the primarily assumed inhibition of androgen biosynthesis…more
  • Functions of PLK1 beyond cell cycle regulation remain poorly characterized which plays important role in the development of various cancers including prostate cancer…more
  • Triethylenetetramine  reveals its potential in cancer chemoprevention and cure of various cancers including prostate cancer…more
  • The study validates role of CX3CR1 in seeding of circulating cancer cells and is expected to pave the way for novel inhibitors of this receptor with current standards of care for the treatment of breast cancer patients…more
  • Mutations and deletions of the Polycomb Repressive Complex 2 (PRC2) complex have been detected in different cancer…more

Prevention of Prostate Cancer

  • Consumption of apples is associated with a reduced risk of cancer in different anatomical sites…more
  • Sun exposure in early life protects against prostate cancer…more
  • Among men with a negative biopsy, aspirin and/or NSAID use was associated with decreased prostate cancer risk…more
  • Grapeseed may be a potential chemopreventive agent in prostate cancer risk…more
  • High frequency of ejaculation is related to decreased risk of total prostate cancer…more
  • Multiple sexual partners may be protective from prostate cancer, excluding the risk of sexually transmitted infections…more

Treatment for Prostate Cancer

  • Comparative effectiveness research for prostate cancer radiation therapy: current status and future directions…more
  • Exercise/physical activity interventions can improve quality of life, fatigue, fitness, and function for men with prostate cancer…more
  • Bisphosphonates have demonstrated efficacy in treating or reducing the risk of skeletal-related events (SREs) in lung cancer, breast cancer, and prostate cancer…more
  • Metformin use appears to be associated with a significant reduction in the cancer risk and BCR of prostate cancer…more
  • Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up…more
  • High-risk prostate cancer—classification and therapy…more

Risk factors for Prostate Cancer

  • Milk consumption is a risk factor for prostate cancer…more
  • Family history of prostate cancer, age, smoking, obesity, consumption of red meat and frequent use of fat items significantly increased the prostate cancer risk…more
  • More consumption of fruit, fluid intake and better lifestyle (physical activity) significantly reduced the risk of developing prostate cancer…more
  • Study shows an association of smoking with prostate cancer incidence and mortality…more
  • Total fat may increase PC risk and tomatoes/tomato products and garlic may protect patients against PC…more
  • Obesity increases the risk of high-grade but decreases the risk of low-grade prostate cancer..more
  • Prostate cancer was found to be increased after folic acid supplementation…more
  • Cd exposure as a risk factor for prostate cancer in occupational rather than nonoccupational populations…more
  • Men with a family history of prostate cancer have a significantly greater risk of developing prostate cancer than those with no such history…more
  • High intakes of dairy products, milk, low-fat milk, cheese, and total, dietary, and dairy calcium, but not supplemental or nondairy calcium, may increase total prostate cancer risk…more

Systematic reviews

  1. Metabolic syndrome is associated with increased risk of common cancers…more
  2. Selenium and prostate cancer: systematic review and meta-analysis…more
  3. Household physical activity is associated with decreased cancer risk in dose-response effect…more
  4. Second malignancies after radiotherapy for prostate cancer: systematic review and meta-analysis…more
  5. Screening for prostate cancer: systematic review and meta-analysis of randomised controlled trials…more

Treatment with Medicinal Herbs

  • Fig (Ficus carica) – Dose, Food farmacy; 30 g fig syrup; steep 2 fruits in wine or booze overnight, then eat on an empty stomach for whooping cough; boil 3 sun-dried leaves for 15 minutes in 300 g water for diabete
  • Garlic (Allium sativum) – Dose, 9-15 g fresh bulb; 0.25-0.5 fresh bulb; 6-12 g dry bulb; 9 g dry bulb: 45 ml alcohol/45 ml water; 1-5 cloves/day; 2-4 g 3 x/day; 4 g garlic or one average clove; 5000 µg allicin/day; 4 g fresh garlic/day

Reference: Handbook of Medicinal Herbs (2006)

Herbals

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