Digital eye

Facts about Myopia

  • Myopia, also known as nearsightedness, is a common type of refractive error where close objects appear clearly, but distant objects appear blurry.
  • Myopia can affect both children and adults. The condition affects about 25 percent of Americans. Myopia is often diagnosed in children between 8 and 12 years of age and may worsen during the teen years.
  • Unlike children in Western populations, where the prevalence of myopia is very low (less than 5%), Asian children have prevalences as high as 29% in 7-year-olds.

Research scope in Myopia

  • Associations between near work activities and myopia have not been consistently observed....more
  • There has been little research examining the psychological antecedents of safety-oriented behavior aimed at reducing myopia risk…..more
  • The study conclude that common variants at chromosome 15q14 influence susceptibility for myopia in Caucasian and Asian populations world-wide…..more
  • Knobloch syndrome is a rare, recessively inherited disorder classically characterized by high myopia, retinal detachment, and occipital encephalocele, but it is now known to have an increasingly variable phenotype. There is a lack of reported electrophysiologic data, and some key clinical features have yet to be described...more
  • Overnight accelerated orthokeratology effectively corrects moderate degree of myopia and provide excellent spectacle free day time vision without any significant adverse effects in the short term...more
  • Open-angle glaucoma (OAG) screening should be performed earlier in participants with high myopia than is suggested by traditional guidelines…..more
  • Older age was significantly related to the rate of change in the visual field (VF) only in myopic glaucomatous eyes….more
  • Clinicians should take into account different postures when excimer laser surgery needs to be performed in patients with myopia during LASIK...more

Treatment for Myopia

  • LASIK appears to have efficacy and safety superior to those of photorefractive keratectomy (PRK)....more
  • The most effective strategy to reduce myopia-related complications is to prevent myopia progression during childhood. Atropine is robust option for childhood myopia control.more
  • Doctors and parents need to be aware that there is a small group of children (younger, with higher myopia, and greater tendency of myopic progression) who may still progress while receiving atropine treatment....more
  • An association between physical activity and myopia was observed, suggesting a protective effect of physical activity on the development and progression of myopia in university students…more
  • Interventions to slow progression of myopia in children….more
  • The efficacy of acupuncture for some diseases is promising and there have been no fatal side effects reported. Further high-quality studies are justified, with five diseases in particular as research priorities…..more

Prevention of Myopia

  • Orthokeratology may slow myopia progression in children...more
  • Carriers of the rs8027411 G allele in the RASGRF1 gene may be at a lower risk of high myopia in Chinese and Japanese populations...more
  • Increasing time spent outdoors may be a simple strategy by which to reduce the risk of developing myopia and its progression in children and adolescents...more
  • Study demonstrate that, with regular instillation, topical 0.05% atropine is an effective agent for controlling myopia progression in a majority of school-aged children for at least a period of 1 year....more
  • Study suggest that intake of a wider variety of plant foods supplying necessary phytochemicals for eye health may help maintain visual acuity and prevent degenerative eye conditions as humans age...more
  • Exposure to Sunlight Reduces the Risk of Myopia in Rhesus Monkeys....more

Risk factors for Myopia

  • Meta-analysis revealed a suggestive association of PAX6 rs644242 with extreme and high myopia, which awaits validation in further studies….more
  • Meta-analysis suggests COL1A1 polymorphisms (rs2075555) is a potential low risk factor for high myopia…more
  • Single-nucleotide polymorphism (SNP) (rs3759223, C→T) in Lumican genemay affect individual susceptibility to high myopia in the Chinese population….more
  • Meta-analysis of existing data revealed a suggestive association of TGFB1 rs1982073 and rs4803455 with high myopia…..more
  • Nonverbal IQ may be an independent risk factor of myopia, and this relationship may not be explained merely by increased reading (books per week) among myopes....more
  • Myopic participants had significantly lower 25(OH)D₃ concentrations. The prevalence of myopia was significantly higher in individuals with vitamin D deficiency compared to the individuals with sufficient levels….more
  • Higher saturated fat and cholesterol intake are associated with longer AL in otherwise healthy Singapore Chinese schoolchildren...more

Systematic reviews

  • Individuals with myopia have an increased risk of developing open-angle glaucoma...more
  • Efficacy Comparison of 16 Interventions for Myopia Control in Children: A Network Meta-analysis...more
  • Individuals with myopia exhibit a decreased risk of developing diabetic retinopathy (DR) or VTDR. An increased axial length (AL) plays a critical role in this protective effect…more
  • There is no significant evidence in scientific literature about the association between computer use and juvenile myopia….more
  • Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050….more
  • The age-specific prevalence of myopia in Asia: a meta-analysis...more

Treatment with Medicinal Herbs

  • Siberian Ginseng (Eleutherococcus senticosus) – Dose – 250-500 ng herb 1-2x/day; 2-16 ml alcoholic extract 1-3x/day up to 60 days; 1-2 droppers herb tincture 2-3x/day 
  • Tiger Lily (Lilium lancifolium) – Dose – 1/8 to 5 drops strong plant tincture 

Reference: Handbook of Medicinal Herbs (2006)


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