Intestinal cancer

Intestinal cancer

Stomach cancer

Facts about Intestinal Cancer

Small intestine is the longest part of the gastrointestinal tract. It represents 75% of its length and 90% of the mucosal surface. Benign tumors are observed at 3-6% and the malignant–1-3% of all cancers of all GI malignancies.

Research scope in Intestinal Cancer

  • SATB2 is not entirely CRC-specific and is expressed in a subset of SIAs. Unlike CRC, however, SIA infrequently shows a strong and diffuse staining pattern, which still makes SATB2 a useful immunomarker to distinguish SIA from CRC....more
  • Familial SI-NETs originate from a subset of EC cells via and increasing understanding of the role of these reserve EC cells in the genesis of multifocal SI-NETs could improve diagnostic and therapeutic strategies for this otherwise intractable disease….more
  • Hypercoagulation has a tumour-promoting effects and it could be used as a new biomarker or as a therapeutic target…..more
  • Activating KRAS and/or BRAF mutations have been identified as predictors of resistance to anti-EGFR chemotherapy in colorectal cancer. But the status of KRAS and BRAF mutations and their clinicopathologic and prognostic significance has not been extensively evaluated in small intestinal adenocarcinomas…more
  • ML264, or an analogue, may hold a promise as a novel therapeutic agent to curb the development and progression of colorectal cancer...more

Treatment for Intestinal Cancer

  • First-line treatment strategies for elderly patients with metastatic colorectal cancer…..more
  • The available treatment modalities for metastatic colorectal cancer are chemotherapy (fluoropyrimidine, oxaliplatin, irinotecan), anti-angiogenic agents (e.g. bevacizumab), and anti-epidermal growth factor agents (cetuximab, panitumumab)..more
  • Practice Guideline for the Surveillance of Patients After Curative Treatment of Colon and Rectal Cancer…..more
  • Laparoscopic colon cancer resection is as safe and efficacious as the conventional open technique...more

Prevention of Intestinal Cancer

  • Combination of selenium and green tea is more effective in suppressing colorectal oncogenesis than either agent alone. ...more
  • Red ginseng extract may be useful for prevention of cancer invasion and metastasis through inhibition of MMP-2 and MMP-9 pathways...more
  • Combination of curcumin and resveratrol could be an effective preventive/therapeutic strategy for colon cancer...more
  • Curcumin in conventional chemotherapeutic regimens could be an effective strategy to prevent the emergence of chemoresistant colon cancer cells....more
  • Polyphenol-rich chocolate foods helps in the prevention of colon cancer….more
  • Soy isoflavone consumption was significantly associated with a reduced risk of CRC risk, particularly with soy foods/products, in Asian populations...more
  • A high intake of dietary fibre, in particular cereal fibre and whole grains, was associated with a reduced risk of colorectal cancer....more

Risk factors for Intestinal Cancer

  • Dietary factors probably are involved in risk of small intestine cancer..more
  • Proximal small bowel disease, 6-mercaptopurine use, and hazardous occupations are associated with cancer of the small bowel in patients with Crohn’s disease and can be added to the list of suspected risk factors….more
  • Alcohol may be associated with an increased risk of small intestine adenocarcinoma risk (SIA)....more
  • Relative risk of colorectal and small bowel cancers are significantly raised in Crohn’s disease….more
  • Overexpression of LPA2 alone can lead to intestinal dysplasia....more

Systematic reviews

  • Systematic review of internet patient information on colorectal cancer surgery....more
  • Most effective colon cancer chemopreventive agents in rats: a systematic review...more
  • Possible better long-term survival in left versus right-sided colon cancer – a systematic review….more
  • Milk and total dairy products, but not cheese or other dairy products, are associated with a reduction in colorectal cancer risk….more
  • Cancer Risk Assessment Tools in Primary Care: A Systematic Review of Randomized Controlled Trials...more
  • Meat subtypes and their association with colorectal cancer: Systematic review and meta-analysis....more

Treatment with Medicinal Herbs

  • Calendula, Marigold, Pot-Marigold (Calendula officinalis)Dose – 5-40 drops tincture 3x/day; 1-5 g herb/cup tea, 3x/daily; 1-4 g flowers as tea, 3x/day; 1-2 flower/cup water
  • Chebulic Myrobalan, (Terminalia chebula)Dose – 3-9 g/day; 1.5-6 g powdered bark; 56-112 ml decoction
  • English Walnut (Juglans regia)Dose – Five tsp chopped leaf/cup water (externally only); 2-3 g leaf/100 ml water for compresses; 4-8 ml liquid leaf extract

Reference: Handbook of Medicinal Herbs (2006)


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