Glaucoma

Glaucoma

Glaucoma

Facts about Glaucoma

  • It is estimated that over 3 million Americans have glaucoma but only half of those know they have it.
  • In the U.S., more than 120,000 are blind from glaucoma, accounting for 9% to 12% of all cases of blindness.
  • African Americans are 15 times more likely to be visually impaired from glaucoma than Caucasians.
  • After cataracts, glaucoma is the leading cause of blindness among African Americans.

Research scope in Glaucoma

  • Disruption of normal IL-20 signaling in the eye may contribute to degenerative processes associated with glaucoma…more 
  • Effectiveness of peripheral laser iridotomy in reducing the development or progression of pigmentary glaucoma is unknown…more
  • Nanotechnological-release delivery of prostaglandin analogues could lower IOP effectively and solve the issue of adherence…more
  • Endogenous and Synthetic Cannabinoids as Therapeutics: new therapy area to treat Glaucoma…more

Treatment for Glaucoma

  • Bimatoprost showed superior efficacy over Latanoprost in lowering intraocular pressure (IOP) in open-angle glaucoma (OAG) patients…detail, more…
  • Latanoprost superior to Timolol in reducing IOP in treatment of patients with primary open angle glaucoma, more…
  • Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension., more…
  • A clinician’s guide to the assessment and management of nonadherence in glaucoma, more…

Prevention of Glaucoma

  • Higher dietary nitrate and green vegetable intake associated with lower POAG risk…more…
  • Five minutes of walking and jogging may help prevent glaucoma by reducing IOP between 56 and 61%, more…
  • Increasing dietary omega-3 reduces IOP with age and help preventing glaucoma…areas…more….

Risk factors for Glaucoma

  • Low socioeconomic status (SES) associated to primary angle closure glaucoma and high more likely to primary open-angle glaucoma (POAG)...more
  • Current smokers are at significantly increased risk of developing POAG…more
  • Obesity, hypertension, and diabetes are associated with IOP and may cause Galucoma….more
  • Mongo ethnic group is associated with an increased risk of OAG…more
  • Individuals with myopia have an increased risk of developing open-angle glaucoma…more

Systematic reviews

  • Comparative Effectiveness of First-Line Medications for Primary Open-Angle Glaucoma: A Systematic Review and Network Meta-analysis…more
  • iStent as a Solo Procedure for Glaucoma Patients: A Systematic Review and Meta-Analysis...more
  • Comparative effectiveness of treatments for open-angle glaucoma: a systematic review for the U.S. Preventive Services Task Force…more
  • Systematic Review of Educational Interventions to Improve Glaucoma Medication Adherence…more
  • Meta-analysis of selective laser trabeculoplasty versus topical medication in the treatment of open-angle glaucoma…more

Treatment with Medicinal Herbs

  • Aloe (Aloe vera) – Dose 50-200 mg powder; 50-300 powder in a single dose at bedtime; 1 tbsp gel 3x/day; 25 mg in 701 mg soyabean oil; 1-2 softgels 3x/day; apply topically; or 1 tbsp juice after meals; Aloe gel, Barbados aloe, and Aloe powder contain respectively 4.87-4.65, and 4.21% aloin, and 2.03% aloe emodin

Reference: Handbook of Medicinal Herbs (2006)

Herbals

TR2Long-term bupropion use may be associated with reduced glaucoma risk

Data from the National Health and Nutrition Examination Survey led researchers to conclude that extended bupropion use could be associated with a reduced risk of glaucoma, according to a study in the British Journal of Ophthalmology. Participants in the National Health and Nutrition Examination Survey (NHANES) are interviewed regarding prescription medications taken in the month preceding the survey. Researchers included all patients older than 40 years who reported the use of bupropion for at least 1 year. Out of 453 participants who self-reported a diagnosis of glaucoma, 108 subjects reported the use of bupropion, of which 3.24% claimed self-reported glaucoma. In those who used bupropion for more than 1 year, self-reported glaucoma decreased compared with those not using bupropion or using it for less than a year, according to the study. More at:http://www.healio.com/optometry

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