Thyroid cancer

Thyroid cancer


Facts about Thyroid Cancer

  • Thyroid cancer is the most common endocrine cancer.
  • The American Cancer Society estimates that there will be about 64,300 new cases of thyroid cancer in the U.S. in 2016.
  • Thyroid cancer is one of the few cancers that has increased in incidence rates over recent years.
  • About 1,980 people (1,070 women and 910 men) will die of thyroid cancer in 2016.

Research scope in Thyroid Cancer

  • Laser ablation using multidirectional-firing fiber could be an effective treatment technique for papillary thyroid carcinoma....more
  • ERα activation seems to exacerbate the development of TC, while wild-type ERβ (ERβ1) plays a protective role against TC....more
  • Mefloquine significantly impairs tumor growth in vivo, highlighting a clear vulnerability of these aggressive, apoptosis-resistant tumors that can be therapeutically exploited...more
  • USP22 as a useful predictor of ATC prognosis and a potential therapeutic target for anaplastic thyroid carcinoma (ATC)..more
  • DUSP4 was identified as a potential biomarker for aggressive behavior in papillary thyroid cancer (PTC), and its overexpression was BRAF(V600E) mutation-related..more
  • miR-486-5p/FBN1 might provide a promising therapeutic target for PTC treatment..more
  • SHARP1 may be an important therapeutic target for the treatment of thyroid cancer...more

Treatment for Thyroid Cancer

  • American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer…more
  • Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.more
  • Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up....more
  • Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review..more
  • Second-line treatment for advanced thyroid cancer: an indication in need of randomized clinical trials...more
  • Guidelines for radioactive therapy of differenciated thyroid cancer..more
  • Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers...more

Prevention of Thyroid Cancer

  • Drinking herbal teas, especially chamomile, protects from thyroid cancer as well as other benign thyroid diseases...more
  • Cigarette smoking and alcohol consumption are associated with reduced risks of papillary thyroid cancer and, possibly, follicular thyroid cancer….more
  • Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway...more
  • Testosterone regulates thyroid cancer progression by reducing tumor suppressor gene expression and tumor immunity...more
  • High consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer...more

Risk factors for Thyroid Cancer

  • Nitrate intake can cause risk of thyroid cancer...more
  • Greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer...more
  • Strong evidence for a dose-response relationship between height and risk of thyroid cancer in both men and women...more
  • Breastfeeding is potentially inversely associated with thyroid cancer risk..more
  • A positive association between seaweed consumption and the risk of thyroid cancer (especially for papillary carcinoma) in postmenopausal women...more
  • Compared with their non-diabetic counterparts, women with pre-existing DM have an increased risk of thyroid cancer...more

Systematic reviews

  • Parity and thyroid cancer risk: a meta-analysis of epidemiological studies...more
  • Sorafenib in radioiodine-refractory differentiated thyroid cancer: a meta-analysis...more
  • The value of miRNA in diagnosing thyroid cancer: a systematic review..more
  • Health-related quality of life among thyroid cancer survivors: a systematic review...more
  • The Effectiveness of Radioactive Iodine Remnant Ablation for Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-analysis...more

Treatment with Medicinal Herbs

  • English Holly (Ilex aquifolium) – Dose – 15-20 g leaf in tea 
  • Goldthread (Coptis spp) – Dose – 0.5-1.2 g powered rhizome; 2-4 ml liquid extract; 1.5-6 g crude drug/day  

Reference: Handbook of Medicinal Herbs (2006)


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