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Sickle Cell Anemia(SCA)

Definition

  • Sickle cell disease (SCD) is a group of inherited red blood cell disorders. People with SCD have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells. Babies are born with sickle cell disease when they inherit two abnormal genes (one from each parent). Hemoglobin is a protein in red blood cells that carries oxygen throughout the body.

Epidemiology and burden of Sickle Cell Anemia

Systematic Reviews

  • Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.more..
  • Neurological complications of sickle cell disease in Africa: protocol for a systematic review.more..
  • Jaundice in neonates with sickle cell disease. A case-control study.more..
  • Depression in children and adolescents with sickle-cell disease.more..
  • Adults with sickle cell disease may perform cognitive tests as well as controls.more..

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